Fulham boss Jean Tigana will have to do without assistant manager John Collins at Deepdale.
The 32-year-old former Celtic and Everton midfielder is struggling with a hamstring injury and will miss out as Cottagers look to avenge their 1-0 loss against the Lilywhites at Craven Cottage earlier in the season.
After the 3-2 win against Derby in the Worthington Cup in midweek, Tigana must decide whether to bring back the five players he rested or stick with the same side that won thanks to Louis Saha's late winner.
Tigana rested Lee Clark, Chris Coleman, Rufus Brevett, Sean Davis and Steve Finnan in midweek as his side set up a clash with Liverpool in the quarter-finals.
Kit Symons, Wayne Collins, Paul Trollope and American international Eddie Lewis were all given their chance and Lewis in particular impressed scoring the second goal.
Fulham already lead the First Division by nine points and they could extend that lead for 24 hours at least as second placed Watford do not face Bolton until SundayPreston have no new injury worries going into their game with Fulham at Deepdale.
Mark Rankine has recovered from an ankle injury and will be available for selection after missing training in the early part of the week.
Former Wolves man Rankine trained on Thursday with no adverse reactions and should be back in David Moyes' plans.
Colin Murdock and Graham Alexander serve the last game of their suspensions, so Gary Parkinson and Michael Jackson will continue to deputise at the back.
American striker Brian McBride is awaiting medical clearance before he can play a contact sport again.
McBride has recovered from a blood clot in his arm and will resume full training when doctors give him the green light.
Source bbcsportonline